重组人白细胞介素2 /Recombinant IL-2，Human，Animal-Free

背景描述：

Interleukin-2 (IL-2) is a 15.5 kDa four bundle, immuno-modulatory cytokine which is expressed predominately by antigen-simulated CD4+ T cells, CD8+ T cells, natural killer (NK) cells, and dendritic cells (DC). IL-2 plays a fundamental role in promoting NK cell proliferation, cytotoxicity, and B cells differentiation. IL-2 modulate T cell differentiation programs, promoting naïve CD4+ T cell differentiation into T helper-1 (Th1) and T helper-2 (Th2) cells.

别称：

interleukin 1 receptor antagonist, ICIL-1RA, IRAP, IL-1RN, IL1RA

蛋白编码：

P60568

分子量：

The protein has a calculated MW of 16.4 kDa. The protein migrates as 13 kDa under reducing condition (SDS-PAGE analysis).kDa

表达系统：

Escherichia coli

纯度：

>98% as determined by SDS-PAGE.

生物活性：

Measure by its ability to induce proliferation in CTLL-2 cells. The ED₅₀ for this effect is <3 ng/mL. The specific activity of recombinant human IL-2 is >5 x 10⁶ IU/mg.

内毒素：

<0.1 EU per 1 μg of the protein by the LAL method.

蛋白序列：

MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT with polyhistidine tag at the C-terminus. 

蛋白标签:

His Tag (C-term)

产品形式:

The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.