重组人白细胞介素4 /Recombinant IL-4，Human，Animal-Free

背景描述：

Interleukin-4 (IL-4) is a key cytokine produced by activated T cells, mast cells, basophils, neutrophils and eosinophils. IL-4 is critical for the development of Th2-mediated responses, which is related to allergy and asthma. It can also regulate B cell responses, including survival, cell proliferation and gene expression. IL-4 also plays fundamental role for B-cell stimulation, including induction of the IgE isotype switch.

别称：

interleukin 4, BCGF, BCDF, B-cell Stimulating Factor (BSF-1), IL4

蛋白编码：

P05112

分子量：

The protein has a calculated MW of 15.9 kDa. The protein migrates as 12 kDa under reducing condition (SDS-PAGE analysis).

表达系统：

Escherichia coli

纯度：

>98% as determined by SDS-PAGE.

生物活性：

Measure by its ability to induce TF-1 cells proliferation. The ED₅₀ for this effect is <0.2 ng/mL. The specific activity of recombinant human IL-4 is approximately >2.8 x 10⁷ IU/mg.

内毒素检测：

<0.1 EU per 1 μg of the protein by the LAL method.

蛋白序列：

MHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS with polyhistidine tag at the C-terminus.

蛋白标签：

His Tag (C-term)

产品形式：

The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0. If you have any concerns or special requirements, please confirm with us.