重组人白细胞介素3 /Recombinant IL-3，Human，Animal-Free

背景描述:

Interleukin-3 (IL-3) is a pleiotropic cytokine which can stimulates the survival, differentiation and proliferation of committed progenitor cells, including megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. IL-3 also enhances phagocytosis and antibody-mediated cellular cytotoxicity. IL-3 binds to IL-3R (IL-3 receptor), which is composed of a unique α subunit (IL-3Rα) and a common β-subunit (βc).

别称:

interleukin 3, MCGF (Mast Cell Growth Factor), Multi-CSF, HCGF, P-cell stimulation factor, Interleukin-3b, IL3

蛋白编码:

P08700

分子量:

The protein has a calculated MW of 16 kDa. The protein migrates as 13 kDa under reducing condition (SDS-PAGE analysis).

表达系统:

Escherichia coli

纯度:

>98% as determined by SDS-PAGE.

生物活性:

Measure by its ability to induce TF-1 cells proliferation. The ED₅₀ for this effect is <0.15 ng/mL. The specific activity of recombinant human IL-3 is approximately >1.2 x 10⁶ IU/mg.

内毒素检测:

<0.1 EU per 1 μg of the protein by the LAL method.

蛋白序列:

MAPMTQTTSLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF with polyhistidine tag at the C-terminus.

蛋白标签:

His Tag (C-term)

产品形式:

The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS,pH 8.0. If you have any concerns or special requirements, please confirm with us.